Introduction: Recurrent Spontaneous Abortion (RSA)is a common occurrence present in approximately 15 to 20% of clinically detectable pregnancies. Recurrent Spontaneous Abortion is still one of the most challenging reproductive issues globally. It is one of the most common pregnancy complications. Recurrent miscarriage refers to two or more miscarriages in a row before the twentieth week of pregnancy. Recurrent Spontaneous abortions are classified into primary and secondary categories. In primary recurrent miscarriages, a successful pregnancy has never occurred, but in secondary cases, recurrent miscarriages occur after live birth. Causes of recurrent miscarriages can be a variety of causes including chromosomal and genetic disorders, anatomical defects, congenital or acquired changes in uterine anatomy, immunological disorders, hereditary thrombophilia, infection, various hormonal disorders, obesity, and true antiphospholipid syndrome. This review article highlights the current understanding of the various etiologies of Recurrent Spontaneous miscarriages, including anatomical defects, genetic disorders, immunological disorders, thrombophilia, and infection.

Study on the livestock diet is one of the main priorities in the management of rangeland in Iran. So, this study was conducted to compare preference values of plant species in three age classes of Kaboudeh sheep (one, three and five year old ones) in rangelands of Bavanat, Fars province, Iran. For each age class, four sheep were selected and their grazing times from different plant species were recorded using a timing method (chronometer) for two hours during the day. The effects of livestock age, plant species and their interactions on preference values of plant species were assessed using a factorial experiment (GLM test). Also, one way ANOVA was applied to compare preference values between plant species for each age class of animals. The results showed that the age of the animals and plant species had significant effects on preference values of plant species. Species of Poa pratensis and Avena fatua for young animals and Acer cinerascens for older animals had higher preference values. In addition, species of Poa pratensis and Prangos ferulaceae had appropriate preference values for all three age classes of animals. As vegetation cover in the study area is mostly consisted of the bushes and shrubs in autumn and on the other hand, sheep has little ability to graze this kind of plant species subsequently during the grazing period, they dominantly focus on herbal species. In general, animal diet demands cannot be provided from rangelands and it is required to use the methods of manual feeding with dry forage and supplements. One of the possible alternatives is to harvest and store the annual yield of P. ferulaceae in spring in order to feed the animals in autumn and winter.

Aim: Assessment of related genes to colon cancer to introduce crucial ones, was the aim of this research. Background: Colon cancer is one of the invasive colorectal diseases. This disease is preventable and manageable if it be diagnosed in early stage. The aggressive tools for its detection imply more investigation for new molecular diagnostic methods. Methods: Numbers of 300 genes from String database (SD) are analyzed via constructed Protein-protein interaction (PPI) network by Cytoscape software 3. 4. 0. Based on centrality parameters the main connected component of network was analyzed and the crucial genes were introduced. Cluster analysis of the network and gene ontology for the nodes of the main cluster revealed more details about the role of the key proteins related to colon cancer disease. Results: The constructed network was consisted of 300 genes which among them 68 genes were isolated and the 232 other genes formed the main connected component. Ten crucial genes related to colon adenocarcinoma were introduced that presented in cluster 1. Gene ontology analysis showed that cluster 1 is involved in 226 biological processes which are classified in 25 groups. Conclusion: In conclusion, results indicate that the identified key proteins play significant roles in colon adenocarcinoma. It may be possible to introduce a few diagnostic biomarker candidates for colon cancer disease.

Biometric recognition is an automatic identification method which is based on unique features or characteristics possessed by human beings and Iris recognition has proved itself as one of the most reliable biometric methods available owing to the accuracy provided by its unique epigenetic patterns. The main steps in any iris recognition system are image acquisition, iris segmentation, iris normalization, feature extraction and features matching. EER (Equal Error Rate) metric is considered the best metric for evaluating an iris recognition system. In this paper, different parameters viz. the scaling factor to speed up the CHT (Circle Hough Transform), the sigma for blurring with Gaussian filter while detecting edges, the radius for weak edge suppression for the edge detector used during segmentation and the gamma correction factor for gamma correction; the central wavelength for convolving with Log-Gabor filter and the sigma upon central frequency during feature extraction have been thoroughly tested and evaluated over the CASIA-IrisV1 database to get an improved parameter set. This paper demonstrates how the parameters must be set to have an optimized Iris Recognition System.

The aim of this research has been to help improve the performance evaluation of physical education teachers by identifying factors involved in such a task and exploring their relevance through a survey of such teachers in Tehran. A cluster sample of 384 physical education teachers was selected from among all such teachers in Tehran’ s 19 districts divided into five geographic areas. Data was collected by distributing and collecting a questionnaire of 47 items on the assessment of physical education teachers, with the internal consistency of 0. 79. Confirmatory factor analysis of the collected data yielded the following results The identified factors are adequately fit to the model wherein the general performance, curricular performance, performance in extracurricular activities, administrative performance, and factors degrading performance were considered as important in evaluation of physical education teachers’ performance. Furthermore, the responding teachers believe that a committee should do such an evaluation at the end of each semester.

A B S T R A C T Green city is one of the approaches to sustainable development. “green city” is an environmentally friendly city compatible with the concept of sustainable development and can be used for the welfare and security of its inhabitants. Based on the concept of a “green city,” urban managers try to have the least destructive effect on the ecosystems upon which cities rely. Green city is one of the sustainable development approaches that reduce the environmental footprint of cities. The purpose of this study is to evaluate the situation of Mashhad metropolis in terms of the objective characteristics of the green city. In this study, 14 indicators of electricity consumption per capita, green space per capita, population density, water availability, sewage availability, superior public transportation network, urban mass transportation, traffic reduction, annual production waste per capita, carbon monoxide, concentration nitrogen dioxide, sulfur dioxide concentration, particulate matter concentration, and air quality were exerted. To determine the importance of research indicators, the Shannon entropy method, and the status of Mashhad city areas in terms of green city indicators, the VIKOR multi-criteria decision-making method has been applied. The results showed that most areas of Mashhad are average and below average in terms of green city characteristics, and only District 9 is in very good condition (0.636). Also, based on the results of this part of the research, District 5, with the value of VIKOR index of 0.969, is in the last rank in terms of objective characteristics of the green city Extended Abstract Introduction Green city is one of the approaches to sustainable development. A “Green city” is an environmentally friendly city compatible with the concept of sustainable development and can be used for the welfare and security of its inhabitants. Based on the concept of a “green city,” urban managers try to have the least destructive effect on the ecosystems upon which cities rely. Green cities constantly try to manage their environmental effects by reducing waste, increasing recycling, reducing air pollution, increasing population density, developing open urban spaces, and encouraging the development of sustainable local businesses. Green cities were first used to evaluate 30 European cities by the Economist Intelligence Unit (EIU) in 2009 with the financial support of Siemens and the aim of reducing the environmental effects of human activities in cities. In that study, eight indices of carbon dioxide, energy, construction, transportation, water, recycling and land use, air quality, and environmental governance were used. Later, the Economist Intelligence Unit, with the financial support of Siemens, evaluated the status of the green city index in 17 Latin American cities, 15 African cities, 22 major Asian cities, and 27 cities in United States, Canada, Australia, and New Zealand. In recent years, even some Western Islamic scholars have, in various publications, shown that Islam is an ecological religion. In Iran, the issue of protecting the environment has not received much attention regardless of its rich cultural and religious background and its confirmation in Article 50 of the Constitution of the Islamic Republic of Iran. Mashhad is the second metropolis of Iran, located in North-East of Iran, and is one of the counties of Khorasan Razavi Province. According to the 2016 Iranian Population and Housing Census, its population was 3057679 people (The Vice-Presidency of Planning and Development of Mashhad Municipality). In Mashhad, due to several reasons including the presence of Imam Reza Shrine (PBUH) and arrival of millions of pilgrims per year, population growth, increased garbage production (production of 896534 tons of garbage in 2016 (The Vice-Presidency of Planning and Development of Mashhad Municipality), air pollution (increased number of unhealthy days from 46 days per year in 2015 to 88 days in 2016 for sensitive groups and 4 days of unhealthy air for all groups in 2016 (Center for Monitoring Environmental Pollutants of Mashhad Municipality) the 2025 vision of the city has paid attention to the environment in the form of five general objectives; however, just like the national level, no specific pattern for environmentally-compatible urban development, such as green city, is determined. Analysis of the green city index in Mashhad metropolis can considerably contribute to urban managers and planners in addition to providing a pattern for evaluating the present situation in other cities of Iran and improving the quality of life regardless of the current status of the urban environment in Iranian cities; we can preserve these environments as parts of the natural environment for future generations.   Methodology In terms of its goal, the present study is an applied one; in the study, drawing upon other studies and library sources and considering the conditions of Iran and the metropolis of Mashhad in terms of green city, 14 quantitative indices were exerted. To this end, the required data for the quantitative indices was gathered by library research from the relevant institutions. Next, the weights of quantitative indices were determined using Shannon's entropy. Then, using the VIKOR method of multi-criteria decision-making, the status of various districts of the metropolis of Mashhad in terms of quantitative indices of green city was determined. Finally, the map of the spatial distribution of quantitative indices was drawn using the ARC GIS software package.   Results and discussion In this study, to analyze the status of the metropolis of Mashhad in terms of green city features, 14 quantitative indices were used. Considering the value of the VIKOR index ranges from 0 to 1, various districts of Mashhad can be classified into five categories; very satisfactory, satisfactory, average, unsatisfactory, and very unsatisfactory in terms of quantitative indices of green city. The results of the current situation of Mashhad showed that in terms of objective indicators of the green city, District 9 of Mashhad metropolis with a value of VIKOR index of 0.056 is in first place, and the seventh region with a value of VIKOR index of 0.433 is in second place. Also, based on the results of this part of the research, District 5, with the value of VIKOR index of 0.969, is in the last rank in terms of objective characteristics of the green city.   Conclusion Similarly, the results of studies by Afshar (2011) and Shabani et al. (2017) on Tehran metropolis are indicative of the unsatisfactory situation of Tehran (the biggest metropolis of Iran) in terms of green city features. Comparing the results of the studies by Afshar (2011) and Shabani et al. (2017) with the present study on Mashhad (the second biggest metropolis of Iran) reveals the necessity for a comprehensive plan toward achieving green cities. It should be mentioned that, due to the specific conditions of Mashhad metropolis and availability or unavailability of the required data, the indices used in the present study are somewhat different from the ones used by Afshar (2011) and Shabani et al. (2017).   Funding There is no funding support.   Authors’ Contribution All of the authors approved the content of the manuscript and agreed on all aspects of the work.     Conflict of Interest Authors declared no conflict of interest.   Acknowledgments We are grateful to all the scientific